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Threshold

Lieutenant Paris makes history by becoming the first person to make a transwarp flight. But soon after his shuttle returns from warp ten he undergoes startling biochemistry changes. His cell membranes begin to degrade and despite the Doctor's best efforts, Paris dies. Hours after the pronouncement of death, Paris is discovered breathing, his body going through accelerated mutations which leave him radically transformed into a bizarre and terrifying cross between a human and amphibian.

Voyager, seizoen 2